1527-89-5 3-Methoxybenzontrile as antipyretic analgesic-tapentadol ingredients

1527-89-5 3-Methoxybenzontrile as antipyretic analgesic - tapentadol ingredients

3-Methoxybenzonitrile, also known as 3-methoxy benzonitrile, m-methoxy benzonitrile, colorless or slightly yellow liquid.

CAS No: 1527-89-5

EC No: 216-201-3

Packaging:200kgs/iron drum with plastic lining

Physical and Chemical Properties

Physical State: Clear liquid

Appearance: colorless - light yellow

Odor: Not available.

pH: Not available.

Vapor Pressure: Not available.

Viscosity: Not available.

Boiling Point: 111.0 - 112.0 deg C @ 13.00mm

Freezing/Melting Point: 0 deg C

Autoignition Temperature: Not available.

Flash Point: 105 deg C ( 221.00 deg F)

Explosion Limits, lower: Not available.

Explosion Limits, upper: Not available.

Decomposition Temperature:

Solubility in water:

Specific Gravity/Density: 1.0890g/cm3

Molecular Formula: C₈H₇NO

Molecular Weight: 133.15

Specifications

Stability and Reactivity
 

Chemical Stability: Stable under normal temperatures and pressures.

Conditions to Avoid: Not available.

Incompatibilities with Other Materials: Strong oxidizing agents.

Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Application

Used as a pharmaceutical intermediate, it is an important intermediate of the new antipyretic analgesic - tapentadol. The drug is mainly used to relieve moderate and severe acute pain, especially for the relief of adults over 18 years of age. Its quick release tablets were approved by the US Food and Drug Administration (trade name: NUCNTA) in November 2008 to relieve moderate and severe acute pain;Its sustained-release tablets were approved for marketing in August 2012 (trade name: NUCYNTA ER) for the treatment of adult diabetic neuropathy (DPN) -related neuropathic pain.In addition, it also can participate in a variety of organic synthesis.

Storage condition

Store in a cool, dry place, avoid direct sunlight. Store in a tightly closed container.

Exposure Controls, Personal Protection

Engineering Controls: Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.

Personal Protective Equipment

Eyes: Wear safety glasses and chemical goggles if splashing is possible.

Skin: Wear appropriate protective gloves and clothing to prevent skin exposure.

Clothing: Not available.

Competitive Advantage

BeiLi is a professional manufacturer of MBN 3-methoxybenzonitrile CAS 1527-89-5 in China

1) We can provide costomers with "one-stop"packaging service,from research,development,production,export and so on.

2) Powerful R&D strength let our technology in a leading level,forever,in turn,to provide customers with better service .

3) We have ISO certificate which let the customers more satisfied and rest assured.

4) More than 20 years of export experience,we can provide customers with more professional service.

5) At the same time, the company has a branch in Shanghai. Shanghai, is one of the world's largest port, convenient for the customes provide logistics services.