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|Synonym:||M-Anisonitrile; AKOS B004087; 3-ANISONITRILE; 3-METHOXYBENZONITRILE;||CAS No:||1527-89-5|
|Appearance:||Colorless Or Pale Yellow Liquid||Purity:||≥99.0%|
|Grade:||Pharmaceutical Grade||Density:||1.089 G/mL At 25 °C|
3-methoxy benzonitrile CAS 1527-89-5 for tapentadol intermediate
3-Methoxybenzonitrile, also known as 3-methoxy benzonitrile, m-methoxy benzonitrile, colorless or slightly yellow liquid.
P/N# : MBN.99P.N
Grade : Pharmaceutical grade
Purity : ≥99.0%
Melting range :
Quality standard : meets company specification
Physical and Chemical Properties
Physical State: Clear liquid
Appearance: colorless - light yellow
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: 111.0 - 112.0 deg C @ 13.00mm
Freezing/Melting Point: 0 deg C
Autoignition Temperature: Not available.
Flash Point: 105 deg C ( 221.00 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Solubility in water:
Specific Gravity/Density: 1.0890g/cm3
Molecular Formula: C8H7NO
Molecular Weight: 133.15
Used as a pharmaceutical intermediate, it is an important intermediate of the new antipyretic analgesic - tapentadol. The drug is mainly used to relieve moderate and severe acute pain, especially for the relief of adults over 18 years of age. Its quick release tablets were approved by the US Food and Drug Administration (trade name: NUCNTA) in November 2008 to relieve moderate and severe acute pain;Its sustained-release tablets were approved for marketing in August 2012 (trade name: NUCYNTA ER) for the treatment of adult diabetic neuropathy (DPN) -related neuropathic pain.In addition, it also can participate in a variety of organic synthesis.
Store in a cool, dry place, avoid direct sunlight. Store in a tightly closed container.
Exposure Controls, Personal Protection
Engineering Controls: Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Personal Protective Equipment
Eyes: Wear safety glasses and chemical goggles if splashing is possible.
Skin: Wear appropriate protective gloves and clothing to prevent skin exposure.
Clothing: Not available.
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